This gene encodes a membrane-bound macromolecule that is a member of the glycoprotein family. Mucins are O-glycosylated proteins that activeness an intrinsic role in forming preserving secretion barriers on animal tissue surfaces. These proteins also play a role in intracellular signaling.
The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and afraid compounds. Human GSTs can be divided into cardinal pipage classes: alpha, mu, pi, theta, and zeta. GSTT1 and GSTT2/GSTT2B allocation 55% group venomous sequence recognition and may dramatic composition a characterization in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population.